A Look At The Side Effects Of Pain Relief & Anti-Inflammatory Drugs

Pain killers and anti-inflammatory drugs are a very useful tool that are used by doctors to help relieve the pain of their patients. Also, you can easily purchase over the counter pain killers without a doctor’s prescription if you suffer from a variety of pains such as headaches, migraines, muscle pains, stomach cramps etc. However, most drugs have side effects, and these can be quite serious, especially over time. It is imperative that you know the side effects of the drugs you take on a regular basis so you can adjust your usage or simply switch to another drug or even a natural remedy.

The most common and popular pain killers are those that are purchased over the counter. Some of these include drugs like ibuprofen, aspirin, naproxen, acetaminophen etc. These types of drugs are usually taken for common pains like fevers and body pains. We will now take a closer look at each drug and their specific side effects.


Aspirin is what is known as a NSAID or non-steroidal anti-inflammatory drug. It is one of the oldest pain relievers known to man and most people use it at some point in their lives. Even though it is an excellent pain reliever, it can cause stomach bleeding if you use it for an extended period of time. This side effect is not unique to aspirin and many other NSAIDs also cause stomach bleeding from prolonged use. It can lead to indigestion and stomach ulcers. If you take a lot of NSAIDs, you can develop kidney damage and it can lead to Reye’s syndrome in children. As a result, you should avoid giving aspirin to children since Reye’s syndrome actually attacks the liver and brain.

However, due to its blood thinning properties, aspirin is often recommended to people who are likely to get a stroke or heart attack. The aspirin works to prevent blood clots, thus preventing stroke. However, it does increase the risk of one type of stroke and that is the one which occurs due to bleeding in the brain.


This drug can be taken on its own and it is also an ingredient in typical sinus and flu tablets and medicines. Fortunately, acetaminophen doesn’t cause stomach issues like aspirin, however, it can cause liver damage, especially if you drink a lot of alcohol while taking it. As a result, you should always check the labels of medicines that you’re taking and follow all of the instructions to prevent any avoidable side effects.


Ibuprofen is a widely used pain killer and just like aspirin and other NSAIDs, it can possibly lead to kidney and stomach problems. However, it is different from aspirin in that it acts faster and actually leaves your body faster which lowers the risk of experiencing any side effects.


This drug is also an NSAID and has the same side effects of aspirin and ibuprofen.

Prescription Based Pain Killers

Now, we will move onto pain killers which require a prescription from your doctor. One of the most powerful of these pain killers are a group of drugs which are known as opioids. They actually prevent you from feeling pain by blocking the nerve signals which transmit information to your brain which makes you feel pain. They actually change what is being transmitted so that you feel pleasure instead. Most doctors only prescribe opioids to people who have to deal with serious pain such as from an extremely painful injury, surgery or if they live with a long term disease such a cancer which causes ongoing pain. Some of the most common opioids include vicodin, codeine, hydrocodone, morphine, oxycodone, meperidine or demerol, propoxyphene or darvon etc.

Another extremely powerful opioid is fentanyl which is actually one hundred times more powerful than any other opioid. This drug is typically only given to people who are suffering from severe pain and are near death such as cancer patients. Unfortunately, this drug has also been abused illegally and mixed with other substances which has resulted in many deaths. We will now take a closer look at the side effects of some of the popular opioids


Vicodin is a combination of acetaminophen and hydrocodone which is used to provide pain relief for moderate to severe pain. Some of the common side effects of using this drug include nausea, anxiety, vomiting, dizziness, drowsiness, constipation, blurred vision, mood changes, problems urinating, dry mouth, ringing ears etc. If you experience any severe side effects such as difficulty breathing, swellings, slow heartbeat, seizures etc, then call your doctor right away.


Codeine is a cough suppressant and pain reliever that is somewhat similar to hydrocodone and morphine. When you take it, a small amount is converted into morphine in your body. By taking codeine, it can increase your tolerance for pain, even though the pain may still be felt. It also causes sedation, drowsiness and slows down breathing. This drug can also be used with aspirin to provide more pain relief. Some of the side effects include dizziness, vomiting, constipation, abdominal pain, itching, rashes, allergic reactions, lightheadedness etc.


This drug is used to relieve moderate to severe pain. It is an opioid analgesic and changes how your body responds to pain. Some popular side effects include nausea and since it is addictive, might cause withdrawal symptoms if stopped prematurely. Some of these include sweating, runny nose, muscle aches, runny eyes, restlessness etc.


This drug is typically used for moderate and even severe pain and is prescribed under the names of Percocet and OxyContin. It can lead to dependence and has a high potential for abuse. Some side effects of this medication include constipation, stomach pain, headaches, mood changes, loss of appetite, dizziness, dry mouth, nausea etc.

In closing, we have just looked at the side effects of the most popular pain relief and anti-inflammatory drugs. It is critical that you take these drugs as prescribed and immediately contact your doctor in the event you experience any severe side effects.  Exploring a different form of pain relief such as StaminaPro and taking a look at!